The good, the bad, and the hazardous: comparative genomic analysis unveils cell wall features in the pathogen Candidozyma auris typical for both baker's yeast and Candida.

The drug-resistant pathogenic yeast Candidozyma auris (formerly named Candida auris) is considered a critical health problem of global importance. As the cell wall plays a crucial role in pathobiology, here we performed a detailed bioinformatic analysis of its biosynthesis in C. auris and related Candidozyma haemuli complex species using Candida albicans and Saccharomyces cerevisiae as references.

Practitioners' Needs for Addressing the Challenges of Sea-Level Rise-A Qualitative Assessment.

Practitioners at the local and regional scale are under increased pressure to reduce risks to people and property posed by the threats of sea-level rise (SLR) and associated impacts. To achieve this, a dialog between practitioners and scientists is imperative. Current research documents impacts of SLR, evaluates local SLR adaptation activities, identifies barriers to action, and works to assess local adaptive capacity.

Recent tropical Andean glacier retreat is unprecedented in the Holocene.

Tropical glaciers have retreated over recent decades, but whether the magnitude of this retreat exceeds the bounds of Holocene fluctuations is unclear. We measured cosmogenic beryllium-10 and carbon-14 concentrations in recently exposed bedrock at the margin of four glaciers spanning the tropical Andes to reconstruct their past extents relative to today. Nuclide concentrations are near zero in almost all samples, suggesting that these locations were never exposed during the Holocene.

Efficacy of the combination of amphotericin B and echinocandins against and in the host model.

Multidrug resistance is a rising problem among non- species, such as . This therapeutic problem has been very important during the COVID-19 pandemic. The World Health Organization has included in its global priority list of health-threatening fungi, to study this emerging multidrug-resistant species and to develop effective alternative therapies.