High resolution signal-averaged ECG (SAECG), echocardiography and 24-hour Holter ECG monitoring were used in the study of 30 patients (mean age 56-/+2 years) with coronary heart disease and stable class II-IV angina (group 1) and 66 patients (mean age 45-/+1 years) with dilated cardiomyopathy of ischemic origin (group II). SAECG was used for detection of late ventricular potentials and calculation of time-voltage and velocity parameters of P-waves. Disturbances of myocardial de- and repolarization indicative of pronounced hemodynamic left atrial overload associated with elevated left ventricular end diastolic pressure were revealed.
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