[Bacterial cutaneous infections in diabetes mellitus and treatment].

Diabetes mellitus (DM) is a debilitating, life-limiting disease. According to recent estimates, 415 million adults currently suffer from the disease. This number is expected to rise to 642 million by 2040.

[Skin aging-cellular senescence : What is the future?].

Background: Cellular senescence is the main cause of skin and organ aging and is associated with a wide range of aging-related diseases.

Objectives: To understand which senolytics, senomorphics, and cell-based therapies have been developed to alleviate and even rejuvenate skin aging and reduce cellular senescence.

Methods: Basic literature for the mode of action of senolytics and senomorphics and their clinical perspectives in daily routine are discussed.

[Skin aging exposome].

The skin is a barrier organ and thus exposed to environmental factors from birth, which essentially determine skin aging. In order to describe and understand this complex process exactly, we applied the concept of the "exposome" to the environmentally induced skin aging process. In this review, we summarize current knowledge on the skin aging exposome.