Primary Kaposi's sarcoma of the heart in non-immunodeficient patient: case report and literature review.

We present a case of Kaposi's sarcoma (KS) of the heart in a 45-year-old non-immunodeficient woman with symptoms of pericardial effusion and cardiac tamponade. Computed Tomography (CT) coronary angiography and transesophageal echocardiography (TEE) showed a low-density tumorous mass (50 mm diameter) at the level of auricle of the right atrium spreading towards the superior vena cava, floating in the cavity of the right atrium. On histological examination, the tumor consisted of fibrovascular connective tissue with areas of necrosis and hemorrhage.

Unusual types of smooth muscle tumors of uterine corpus: case reports and literature review.

Classification of a smooth muscle neoplasm as benign or malignant is straightforward. Morphologic and biologic diversity makes smooth muscle neoplasia a diagnostic dilemma for pathologists but fascinating area of study. We report three cases of unusual types of smooth muscle tumors of uterine corpus: 1) highly cellular leiomyoma; 2) cotyledonoid dissecting leiomyoma (CDL) and 3) poorly differentiated leiomyosarcoma.

[Morphological criterion in the spleen organ-preserving experimental surgery].

Thrombosis and inflammatory complications are concomitant to the post-surgery period of splenectomy due to the traumatic damage to the spleen. Therefore morphological analysis of the spleen residue after the partial spleen resection is of particular theoretical and practical interest. Total of 36 white rats, male, body mass 130-150 g.

Wnt signaling in prostate development and carcinogenesis.

Background: The Wnt signaling pathway is crucial for cell fate decisions, stem cell renewal, regulation of cell proliferation and differentiation. Deregulated Wnt signaling is also implicated in a number of hereditary and degenerative diseases and cancer.

Methods And Results: This review highlights the role of the Wnt pathway in the regulation of stem/progenitor cell renewal and prostate gland development and how this signaling is altered in prostate cancer.

[Immunohistochemical investigation of steroid hormones (ER, PR) in breast cancer].

Immunohistochemical investigations were performed in 22 cases of breast cancer. The objective of this study was to assess the presence and distribution of ER and PR in the cancer tissue. We found that expression of the ER and PR in the cancer tissue is variable, which depends on cancer histogenesis (lobular, ductal), histological form, differentiation grade, and stage of its development.