Publications by authors named "E Maguin"
Background: In recent years, human microbiome research has flourished and has drawn attention from both healthcare professionals and general consumers as the human microbiome is now recognized as having a significant influence on human health. This has led to the emergence of companies offering microbiome testing services. Some of these services are sold directly to the consumer via companies' websites or via medical laboratory websites.
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- The gut microbiota and their metabolites are crucial in regulating host physiology, and diet plays a significant role in influencing microbiota composition and functionality.
- A study was conducted on semi-stray dogs in Tunisia to assess how switching from a natural diet to an industrial kibble diet affected their fecal microbiota, short-chain fatty acid (SCFA) levels, bile acids, and protease activities.
- Results showed that the dietary change led to a decrease in primary bile acids and protease activities, while changes in specific microbial genera were linked to improved physiological parameters, highlighting the importance of diet in shaping the microbiome and its functions.
Article Synopsis
- Human microbiomes play a crucial role in health by impacting metabolism, immune functions, and neurological processes, but their complete complexity is still not fully understood.
- The definition of a "healthy" microbiome is controversial due to variations in microbial communities and the difficulty in establishing a standard definition for health across different individuals and conditions.
- The article highlights progress in microbiome research and identifies gaps in knowledge, proposing a roadmap that utilizes epidemiological methods to better understand the relationship between microbiomes and health.
In recent years, microbiomes and their potential applications for human, animal or plant health, food production and environmental management came into the spotlight of major national and international policies and strategies. This has been accompanied by substantial R&D investments in both public and private sectors, with an increasing number of products entering the market. Despite widespread agreement on the potential of microbiomes and their uses across disciplines, stakeholders and countries, there is no consensus on what defines a microbiome application.
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