Publications by authors named "E Magliulo"
Background: Complement 3 (C3) glomerulopathy (C3G) is a heterogenous disease characterized by dysregulation of the complement alternative pathway. Within 10 years of a diagnosis, roughly 50% of patients with C3G will progress to end-stage kidney disease. Historically, treatment options have been limited to nonspecific immune suppression with suboptimal response rates to recommended therapies.
View Article and Find Full Text PDFEnd stage kidney disease (ESKD) patients until recently have been effectively excluded from receiving hospice benefits unless they withdraw from renal replacement therapy. Policy change has allowed select populations to receive concurrent hospice and hemodialysis. We conducted a retrospective analysis of all deaths occurring from 2019 to 2022 among outpatient hemodialysis patients at our VA medical center.
View Article and Find Full Text PDFArticle Synopsis
- Research discusses how current global climate models are based on air temperatures but fail to capture the soil temperatures beneath vegetation where many species thrive.
- New global maps present soil temperature and bioclimatic variables at 1-km resolution for specific depths, revealing that mean annual soil temperatures can differ significantly from air temperatures by up to 10°C.
- The findings indicate that relying on air temperature could misrepresent climate impacts on ecosystems, especially in colder regions, highlighting the need for more precise soil temperature data for ecological studies.
[Anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis] (AAV) is an autoimmune disease characterized by systemic vascular inflammation. We present a case of a 76-year-old man who presented with shortness of breath, fatigue, and weakness. He was eventually diagnosed with hydralazine-induced ANCA-associated renal limited glomerulonephritis.
View Article and Find Full Text PDFSensitivity of gross primary productivity to climatic drivers during the summer drought of 2018 in Europe.
Philos Trans R Soc Lond B Biol Sci
October 2020
Article Synopsis
- In summer 2018, Europe experienced a record drought, which significantly reduced gross primary productivity (GPP) in ecosystems, with grasslands suffering a -38% decline while forests saw a -10% decline.
- Observations revealed that the drought led to greater sensitivity of GPP to environmental factors, with stronger negative effects from summer air temperature and vapor pressure deficit compared to a normal summer in 2016.
- The study highlights how higher temperatures and reduced soil water content during the drought severely impacted ecosystem carbon dynamics, indicating a worsening scenario for plant productivity in drought conditions.