Publications by authors named "E Madan"
Article Synopsis
- The study investigates how cancer cells influence the fitness of surrounding tumor microenvironment (TME) cells through a mechanism involving a long non-coding RNA called Tu-Stroma, which alters the expression of Flower isoforms, impacting their growth advantage.
- The expression of Flower Win isoforms in cancer cells enhances their dominance over TME cells that express Flower Lose isoforms, leading to reduced fitness in the TME.
- Targeting Flower proteins with a humanized monoclonal antibody in mice has shown promising results, significantly reducing cancer growth and metastasis while improving survival rates and protecting organs from potential lesions.
Leishmaniasis is a parasitic disease caused by various species of the Leishmania parasite, manifesting in visceral (VL), cutaneous (CL), and mucocutaneous (MCL) forms. To combat this debilitating disease, various vaccines candidates including proteins, DNA, vectors, adjuvants, and recombinant whole parasites have been developed and tested experimentally and preclinically against several Leishmania species. Some vaccines have already entered human clinical trials.
View Article and Find Full Text PDFRank Ordered Design Attributes for Health Care Dashboards Including Artificial Intelligence: Usability Study.
Online J Public Health Inform
November 2024
Background: On average, people in the United States visit a doctor 4 times a year, and many of them have chronic illnesses. Because of the increased use of technology, people frequently rely on the internet to access health information and statistics. People use health care information to make better-educated decisions for themselves and others.
View Article and Find Full Text PDFIntroduction: Mouthwashes are highly efficacious chemical agents for managing plaque and gingivitis. The aim of the present study was to evaluate and compare the efficacy of turmeric (TM) and chlorhexidine (CHX) mouthwash as anti-plaque and anti-gingivitis agents.
Materials And Methods: This retrospective, observational study was conducted on the clinical case records of 60 patients with gingival and plaque scores of ≥ 1, who were treated with TM mouthwash as group 1 and CHX mouthwash as group 2 for a period of two months.
Introduction: Mouth rinse is a highly effective chemical solution for managing plaque and gingivitis. This study evaluated and compared the efficacy of chitosan (CH)-rich mouthwash with standard chlorhexidine (CHX) mouthwash in reducing gingivitis, plaque, halitosis, and stains.
Materials And Methods: This retrospective, observational study was conducted on the clinical case records of 60 patients who were treated with CH mouthwash (formulated and dispensed from the department) as group 1 and CHX mouthwash as group 2 for at least three months.