Effect of bariatric endoscopy on liver fibrosis and steatosis and the course of NAFLD - a prospective interventional study.

Introduction And Objectives: With increases in obesity and metabolic syndrome because of lifestyle-related factors, the prevalence of non-alcoholic fatty liver disease (NAFLD) also is increasing worldwide. In a subset of patients with NAFLD, an inflammatory process arises in the steatotic liver, known as non-alcoholic steatohepatitis, that leads to liver fibrosis and liver cirrhosis. In selected patients with obesity, bariatric surgery, and bariatric endoscopy are important therapeutic options.

Endoscopic extraction of a loose Fobi ring in a patient with gastric bypass.

Obesity has become a worldwide problem with a growing incidence, posing a risk to health, especially for cardiovascular disease, diabetes, certain types of cancer, depres-sive syndrome, and others. The methods of obesity treatment are still expanding, in addition to diet and exercise measures, pharmacological, endoscopic and surgical treatment is possible. One of the commonly performed bariatric surgical procedures is the Roux-en-Y gastric bypass, which combines restrictive and malabsorptive effects.

Endoscopic sleeve gastroplasty - where we are and where we are heading.

Obesity is a global problem with a rising prevalence, which has serious implications not only for individuals' health but also for society as a whole. The increased incidence of overweight and obesity leads to higher healthcare costs and limits the employment opportunities of individuals, affecting their quality of life. The treatment of obesity encompasses various approaches, including diet, exercise, pharmacotherapy, and surgical bariatric procedures.