Publications by authors named "E Machacova"
Article Synopsis
- Laser-induced breakdown spectroscopy (LIBS) enhances immunochemical assays using indirect label detection with nanoparticles, specifically yttrium-based photon-upconversion nanoparticles (UCNPs), achieving sensitivity comparable to established methods like fluorescence immunoassays.
- The study improves the sensitivity of UCNP-based Tag-LIBS by incorporating magnetic microbeads (MBs), which allow for analyte preconcentration and significantly lowers the limit of detection (LOD) to 4.0 pg/mL, a notable advancement over traditional microtiter plate methods.
- The technique demonstrates robust performance in clinical samples and shows strong correlation with standard assays, indicating that MB-based Tag-LIBS offers fast readout, high sensitivity, and potential for multiplexing without relying
Environmental tobacco smoke (ETS) exposure has been shown in general as a major environmental risk factor and deserves attention in vulnerable population groups. The aim of the project is to analyze the relationships among the ETS and behavior and health in 6−15-year-old children in Slovakia. The status of physical and mental health of children in relation to exposure to tobacco smoke was examined in a representative group of 1478 school children.
View Article and Find Full Text PDFLong-term trends in the epidemiology of human leptospirosis (Slovak Republic, 1954-2006).
Eur J Clin Microbiol Infect Dis
September 2012
The purpose of this study was the observation of eventual shifts in some basic epidemiological features of human leptospirosis in Slovakia over a long period of time. Epidemiological traits of human leptospirosis were evaluated in three decades: 1954-1963 (822 cases), 1976-1985 (477 cases) and 1997-2006 (310 cases). The evaluation encompassed the aetiologic structure of cases, the incidence rate of diseases, men-to-women ratio of patients, as well as the professional and seasonal distribution of patients.
View Article and Find Full Text PDF[Results of surveillance of human leptospirosis in Slovakia 1986-2005].
Epidemiol Mikrobiol Imunol
August 2007
Study Objective: Presentation of results of surveillance of human leptospirosis over the last 20 years.
Material: The data sources were the annually published results of leptospirosis surveillance and study of natural focuses of these infections.
Results: We describe trends in the overall incidence of leptospirosis, distribution of cases by etiological agent and type of leptospirosis, morbidity rate, distribution of patients with different types of leptospirosis by age and occupation/socio-economic group, leptospirosis seasonality and clinical forms.