Publications by authors named "E MacLaren"

We set out to understand whether MedNav, a digital decision support tool, improves the quality of neonatal resuscitation practice in resource poor settings. A 6-month long trial in Uganda showed that adherence to good practice increased from a mean of 46% without MedNav to 94% with MedNav. The mean system usability score was self-assessed at 84.

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Article Synopsis
  • Schizophrenia and bipolar disorder are brain diseases linked to several genes that mess up how brain circuits work.
  • Scientists have created a special system to study how these genes affect the brain’s nerve connections and tested proteins related to schizophrenia and bipolar disorder.
  • Their findings show that different genes can change how brain networks behave and that these changes can lead to important differences in how the brain works.
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Background: LMO4 is a transcription cofactor expressed during retinal development and in amacrine neurons at birth. A previous study in zebrafish reported that morpholino RNA ablation of one of two related genes, LMO4b, increases the size of eyes in embryos. However, the significance of LMO4 in mammalian eye development and function remained unknown since LMO4 null mice die prior to birth.

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