Novel Fluorescent Tetrahedral Zinc (II) Complexes Derived from 4-Phenyl-1-octyl-1-imidazole Fused with Aryl-9-Carbazole and Triarylamine Donor Units: Synthesis, Crystal Structures, and Photophysical Properties.

We present here the design, synthesis, and photophysical properties of two novel fluorescent zinc (II) complexes, () and (), containing 4-(1-octyl-1-imidazol-4-yl)-,-diphenyl-[1,1-biphenyl]-4-yl)-4-amine and 9-(4-(1-octyl-1-imidazol-4-yl)-[1,1-biphenyl]-4-yl)-9-carbazole ligands. The newly synthesized free ligands and their zinc (II) complexes were characterized using several spectroscopic techniques; their structures were identified by single-crystal X-ray diffraction; and their photophysical properties have been studied in the context of their chemical structure. The () and () complexes showed good thermal stability at 341 °C and 365 °C, respectively.

A Review: Blue Fluorescent Zinc (II) Complexes for OLEDs-A Last Five-Year Recap.

Blue emissions in organic light-emitting diodes (OLEDs) are essential for their application in solid-state lighting and full-colour flat panel displays. On the other hand, high-power blue emitters are still uncommon, especially those that can achieve the Commission Internationale de l'Eclairage (CIE, X, Y) coordinates of (0.14, 0.

Catalyst-free synthesis of novel 1,5-benzodiazepines and 3,4-dihydroquinoxalines using isocyanide-based one-pot, three- and four-component reactions.

Reaction of benzimidazolone derivatives, or their thio- or aza-counterparts, with an isocyanide in the presence of acetone unexpectedly gave rise to novel tricyclic benzodiazepine derivatives in good yield by means of a four-component reaction incorporating two moles of acetone. Benzimidazole starting substrates bearing an electron-withdrawing group gave rise instead to dihydroquinoxaline derivatives by means of a three-component reaction. Use of deuterated acetone instead of acetone in the reactions significantly affected yield and reactivity in the four-component reaction but not in the three-component reaction.

Studies towards the Design and Synthesis of Novel 1,5-Diaryl-1-imidazole-4-carboxylic Acids and 1,5-Diaryl-1-imidazole-4-carbohydrazides as Host LEDGF/p75 and HIV-1 Integrase Interaction Inhibitors.

Two targeted sets of novel 1,5-diaryl-1-imidazole-4-carboxylic acids and carbohydrazides were designed and synthesized from their corresponding ester intermediates , which were prepared via cycloaddition of ethyl isocyanoacetate and diarylimidoyl chlorides . Evaluation of these new target scaffolds in the AlphaScreen HIV-1 IN-LEDGF/p75 inhibition assay identified seventeen compounds exceeding the pre-defined 50% inhibitory threshold at 100 µM concentration. Further evaluation of these compounds in the HIV-1 IN strand transfer assay at 100 μM showed that none of the compounds (with the exception of , , and , with marginal inhibitory percentages) were actively bound to the active site, indicating that they are selectively binding to the LEDGF/p75-binding pocket.