Publications by authors named "E M Tay"
Transcatheter aortic valve implantation (TAVI) has been established as an effective treatment modality in patients with severe aortic stenosis (AS) and the uptake of TAVI is rapidly growing in the Asia-Pacific region. However, there exist a heterogeneity in the management of aortic stenosis and the use of TAVI among countries in the region. Reasons for these differences include anatomic variations, disparity in healthcare resources and infrastructure, and the lack of consensus on the optimal management of AS in the Asia-Pacific region.
View Article and Find Full Text PDFDisseminated venous thromboembolism (VTE) occurs commonly in cancer patients, who tend to have contraindications to systemic thrombolysis and require cancer surgery. Such clinical scenarios are often challenging to manage. In this case report, we illustrate an innovative, single procedural approach in such a patient to remove extensive VTE, improve symptoms, prevent hemodynamic decompensation, and allow for a minimal level of anticoagulation such that necessary cancer surgery can proceed safely.
View Article and Find Full Text PDFSingle and Dual Task Gait Speed in Frailty Screening of Community-Dwelling Older Adults.
J Prim Care Community Health
December 2024
Objective: This study compares dual task (DT) gait speed between robust and frail older adults in the setting of a community-based frailty screening program.
Methods: A cross-sectional study was conducted involving older adults aged 50 years or older. Participants were categorized as robust, pre-frail or frail using the FRAIL phenotype.
Article Synopsis
- Embryonic stem cells can self-organize into structures similar to blastocysts, which are important for studying early development and potential therapies.
- Researchers identified key factors influencing blastoid formation, focusing on the gene Nr1h2, which is critical for its development and operation across multiple species.
- Activation of Nr1h2 not only promotes blastoid creation but also enhances their ability to implant in the uterus and contribute to both embryonic and extraembryonic tissues, highlighting its broad regulatory role in early embryonic development.
Background: At the onset of the Coronavirus disease (COVID-19) pandemic when pharmaceutical interventions were not readily available, governments relied on public health mandates and social distancing measures to counter rising infection rates. In order to address the dearth of longitudinal studies, this study sought to identify factors associated with continued adherence to COVID-19 preventive behaviours in Singapore.
Methods: Data were from a two-wave longitudinal cohort study; baseline study was conducted from May 2020 to June 2021 and follow-up study from October 2021 to September 2022.