Publications by authors named "E M Savilahti"
Article Synopsis
- - This study compares human milk antibodies to various pathogens in women from five different countries (Bangladesh, Finland, Peru, Pakistan, and the U.S.) using advanced protein microarrays, analyzing samples from 695 women.
- - Results reveal that antibody levels, specifically IgA and IgG, vary significantly by region and are influenced by factors like maternal BMI and number of children, with the highest antibody coverage found in Bangladeshi and Pakistani mothers.
- - The findings suggest that certain human milk antibodies may provide protective benefits against infections in infants, which could inform strategies to reduce infant illness and mortality globally.
Background/objectives: Milk is an important source of dietary calcium and, if fortified, vitamin D. Cow's milk allergy (CMA) is treated with a milk elimination diet. Although most children become tolerant by age 3 years, some continue dairy avoidance.
View Article and Find Full Text PDFBackground: The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) (NCT00179777) found no difference type 1 diabetes risk between hydrolyzed and regular infant formula. However, cow milk consumption during childhood is consistently linked to type 1 diabetes risk in prospective cohort studies.
Objectives: Our primary aim was to study whether humoral immune responses to cow milk and cow milk consumption are associated with type 1 diabetes in TRIGR children.
Perinatal and early-life factors reported to affect risk of allergic diseases may be mediated by changes in the gut microbiota. Here, we explored the associations between the infant gut microbiota and allergic morbidity in childhood until 13 years of age in a subgroup of the FLORA probiotic intervention cohort. A mixture of four probiotic strains with galacto-oligosaccharides was administrated to the mothers from the 36th week of the pregnancy and later to their infants until 6 months of age.
View Article and Find Full Text PDFBackground: Urban-related nature exposures are suggested to contribute to the rising prevalence of allergic diseases despite little supporting evidence. Our aim was to evaluate the impact of 12 land cover classes and two greenness indices around homes at birth on the development of doctor-diagnosed eczema by the age of 2 years, and the influence of birth season.
Methods: Data from 5085 children were obtained from six Finnish birth cohorts.