Cytologic characteristics of tubulolobular carcinoma of the breast.

Objective: To determine the cytologic characteristics of tubulolobular carcinoma, a rare tumor of the breast in which the histologic features of both tubular and lobular carcinoma are combined.

Study Design: Review of fine needle aspirates and corresponding intraoperatively prepared touch imprints of eight cases of tubulolobular carcinoma.

Results: Low nuclear grade of tumor cells, low mitotic activity, intracytoplasmic vacuoles, single filing of cells and presence of tubular structures were observed in both preparations in most cases.

Fine-needle aspiration of breast biopsy specimens: correlation of histologic and cytologic findings.

The accuracy of fine-needle aspiration (FNA) cytologic diagnosis of nonpalpable breast lesions and the prevalence of neoplasm occurring in areas unrelated to the radiologic abnormality were studied. Template-guided FNA cytologic examination was performed in 101 surgically excised breast specimens. The exact area of the mammographic abnormality was aspirated with radiographic control.