Rock Steady Boxing: A qualitative evaluation of a community exercise program for people with Parkinson's disease.

Purpose: Regular exercise can reduce the symptoms of Parkinson's disease, a common neurodegenerative disorder. The Rock Steady Boxing organization created an exercise program for people with Parkinson's Disease (pwPD) modelled after traditional boxing. The purpose of this study was to better understand the physical function, exercise beliefs, contextual factors, class experiences and outcome perceptions of pwPD participating in Rock Steady Boxing.

Spin transport of a doped Mott insulator in moiré heterostructures.

Moiré superlattices of semiconducting transition metal dichalcogenide heterobilayers are model systems for investigating strongly correlated electronic phenomena. Specifically, WSe/WS moiré superlattices have emerged as a quantum simulator for the two-dimensional extended Hubbard model. Experimental studies of charge transport have revealed correlated Mott insulator and generalized Wigner crystal states, but spin transport of the moiré heterostructure has not yet been sufficiently explored.

HHIP's Dynamic Role in Epithelial Wound Healing Reveals a Potential Mechanism of COPD Susceptibility.

A genetic variant near has been consistently identified as associated with increased risk for Chronic Obstructive Pulmonary Disease (COPD), the third leading cause of death worldwide. However HHIP's role in COPD pathogenesis remains elusive. Canonically, HHIP is a negative regulator of the hedgehog pathway and downstream GLI1 and GLI2 activation.

Unlocking mitochondrial dysfunction-associated senescence (MiDAS) with NAD - A Boolean model of mitochondrial dynamics and cell cycle control.

The steady accumulation of senescent cells with aging creates tissue environments that aid cancer evolution. Aging cell states are highly heterogeneous. 'Deep senescent' cells rely on healthy mitochondria to fuel a strong proinflammatory secretome, including cytokines, growth and transforming signals.