Publications by authors named "E M Ratner"
Background: Uterine teratomas are a rare entity with a debated origin. Given its rarity and limitations of diagnostic imaging, diagnosis is typically determined pathologically following surgical resection based on the presence of tissue derived from all germ cell layers. Unlike its ovarian counterpart, the developmental origins are poorly understood; however, recently introduced molecular testing has revolutionized our understanding of these rare tumors.
View Article and Find Full Text PDFPatient sexuality and intimacy comprise important dimensions of quality of life (QOL), making them essential topics for palliative care (PC) clinicians to address. Created with interprofessional input from PC, urology, gynecology, sexual health, oncology, psychiatry, psychology, nursing, and social work, this article offers 10 high-yield, evidence-based tips to better equip PC clinicians to address sexuality and intimacy for patients with serious illness. These tips highlight skills such as opening discussions, assessing concerns through a biopsychosocial model, and thinking through appropriate interventions to improve QOL.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated the effectiveness of ixabepilone (IXA) combined with bevacizumab (BEV) in treating ovarian cancers resistant to paclitaxel, revealing that the combination therapy significantly improves overall response rates (ORR) and progression-free survival (PFS) compared to ixabepilone alone.
- - A phase 2 clinical trial randomly assigned 76 patients, showing that those receiving IXA + BEV had a much higher ORR (38.4% vs. 8.1%) and greater PFS (5.5 months vs. 2.2 months) and overall survival (OS) (10.3 months vs. 6.0 months) despite many participants requiring
Article Synopsis
- - The NCCN Guidelines outline a comprehensive approach to diagnosing, staging, and treating ovarian, fallopian tube, and primary peritoneal cancers.
- - Recent developments in the use of PARP inhibitors, both as maintenance therapy and standalone treatments, have significantly influenced the recommendations in these guidelines.
- - These insights highlight the collaborative effort among experts to continuously update treatment protocols based on the latest research in ovarian cancer therapies.
Older adults were disproportionately affected by COVID-19. The purpose of this study was to explore experiences of sudden-onset social isolation and factors that influenced it among social isolation in two groups of older adults. A qualitative thematic study with a survey component was conducted comparing 18 older adults in two groups: 12 reporting physical health challenges and 6 reporting no physical health challenges.
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