Publications by authors named "E M Quartuccio"
Objective: Multiple sclerosis (MS) is a complex disorder in which environmental and genetic factors interact modifying disease risk and course. This multicentre, case-control study involving 18 Italian MS Centres investigated MS course by ethnicity and native-country economic status in foreign-born patients living in Italy.
Methods: We identified 457 MS patients who migrated to Italy and 893 age- and sex-matched native-born Italian patients.
Article Synopsis
- - The study evaluated the safety and effectiveness of moderately hypofractionated helical tomotherapy (HT) for treating localized prostate cancer in 170 patients over a median follow-up of 36 months.
- - Patient risk levels varied, with 34% classified as low risk, 30% as intermediate risk, and 36% as high risk, and the treatment involved significant radiation doses to the prostate and surrounding areas.
- - The results showed that most patients experienced mild to no side effects, with 2- and 3-year biochemical relapse-free survival rates of 90% and 87.5%, and overall survival rates of 96.4% and 90%, respectively.
Objective: To test a possible benefit of dalfampridine on information processing speed (IPS), a key function for cognitive impairment (CogIm) in multiple sclerosis (MS).
Methods: In this randomized, double-blind, placebo-controlled trial, we included patients with a score on the Symbol Digit Modalities Test (SDMT) under the 10th percentile of the reference value. Patients were randomized in a 2:1 ratio to receive dalfampridine 10 mg or placebo twice daily for 12 weeks.
Background/aim: Pineoblastoma of the adult age is an uncommon tumor with only 200 cases reported. A standardized approach for an optimal adjuvant strategy is currently lacking. The case presented herein also deals with the issue of central nervous system tumors in pregnancy.
View Article and Find Full Text PDFMultiple sclerosis (MS) is a primary inflammatory demyelinating disease associated with a probably secondary progressive neurodegenerative component. Impaired mitochondrial functioning has been hypothesized to drive neurodegeneration and to cause increased anaerobic metabolism in MS. The aim of our multicentre study was to determine whether MS patients had values of circulating lactate different from those of controls.
View Article and Find Full Text PDF