Publications by authors named "E M Piredda"

Article Synopsis
  • The study investigates the best timing for performing percutaneous coronary interventions (PCI) in patients undergoing transcatheter aortic valve implantation (TAVI), a procedure for severe aortic stenosis with existing coronary artery disease (CAD).
  • An analysis of 1,603 patients from the REVASC-TAVI registry shows that performing PCI after TAVI leads to better 2-year clinical outcomes, with significantly lower rates of all-cause death and major complications compared to PCI before or concurrently with TAVI.
  • The findings suggest that scheduling PCI after TAVI may be more beneficial, but further confirmation through randomized clinical trials is needed.
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Objective: Acute kidney injury (AKI) may complicate transcatheter aortic valve replacement (TAVR) and could be linked to atheroembolization associated with catheter manipulation in the supra-renal (SR) aorta. We sought to determine the impact of SR aortic atheroma burden (SR-AAB) and composition, as well as of the aortic valve calcium score (AV-CS), measured at pre-operative multislice computed tomography (PO-MSCT), on AKI-TAVR.

Methods: All TAVR-patients 3 January-2018 to December-2020 were included.

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Article Synopsis
  • The study assesses the management of stable coronary artery disease (CAD) in patients undergoing transcatheter aortic valve implantation (TAVI), highlighting inconsistencies in existing evidence.
  • Using data from the REVASC-TAVI registry with 2407 patients, researchers compared outcomes between those who underwent complete versus incomplete myocardial revascularization.
  • Findings indicate no significant differences in all-cause death or composite outcomes (like stroke and rehospitalization for heart failure) between the two groups after 2 years, suggesting that the completeness of revascularization may not impact outcomes for TAVI patients with stable CAD.
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Article Synopsis
  • * Identifying the underlying causes of MINOCA is essential for effective patient care, as it involves various pathological conditions and differs in risk factors compared to traditional myocardial infarction cases.
  • * The presence of atypical risk factors like anxiety, depression, and autoimmune diseases is more common in MINOCA patients, but research on these factors is limited and inconsistent, highlighting the need for comprehensive studies.
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