Importance of plasma angiotensin concentrations in a comparative study of responses to angiotensin in the maturing newborn lamb.

Plasma angiotensin concentrations were measured in a longitudinal study of the vascular, renal, and adrenal responses to infusions of angiotensin II (AII) in the maturing newborn lamb. Basal plasma concentrations of angiotensin increased with age and correlated with the rising arterial pressure that occurred with maturation. However, age was a stronger determinant of arterial pressure than was plasma angiotensin concentration.

Decreased plasma and urinary dopamine during dietary sodium depletion in man.

This study was designed to investigate the influence of dietary sodium restriction on plasma and urine dopamine levels. Five normal white male volunteer subjects wee studied in metabolic balance at constant 150 meq sodium, 60 meq potassium intake and then daily for 7 days on an isocaloric constant diet of 10 meq sodium and 60 meq potassium/day. With dietary sodium restriction, urinary sodium excretion decreased from 152 +/- 13 meq/day in stepwise fashion to 7 +/- 1 meq/day (P less than 0.

Dopaminergic inhibition of metoclopramide-induced aldosterone secretion in man. Dissociation of responses to dopamine and bromocriptine.

This study was designed to investigate the role of dopaminergic mechanisms in the control of aldosterone secretion in man. Five normal male subjects in metabolic balance at 150 meq sodium/d and 60 meq potassium/d constant intake received the specific dopamine antagonist, metoclopramide, 10 mg i.v.

Effects of metoclopramide and bromocriptine on the renin-angiotensin-aldosterone system in man. Dopaminergic control of aldosterone.

This study was designed to investigate the possible role of dopaminergic mechanisms in the control of the renin-angiotensin-aldosterone system in normal man. Six normal male subjects in metabolic balance at 150 meq sodium, 60 meq potassium constant intake received the specific dopamine antagonist, metoclopramide, 10 mg i.v.