Publications by authors named "E M Neeman"
Indane-based molecules are effective scaffolds for different pharmaceutical products, so it is relevant to analyze the relation between structure and functionality in indane derivatives. Here, we have characterized the conformational landscape and molecular structure of 1-aminoindane in the gas phase using chirped-excitation Fourier-transform microwave spectroscopy and computational methods. The rotational spectrum confirmed the presence of two conformers, which were identified based on their rotational constants and 14N nuclear quadrupole coupling tensor elements.
View Article and Find Full Text PDFBackground: Widespread adoption of secure messaging (SM) provides patients with cancer with unprecedented access to medical providers at the expense of increased workload for oncologists. Herein, we analyze oncology SM clinical content and acuity and translate these to estimated cost savings from reduced appointments.
Methods: This population-based retrospective cohort study examined the content of patient-initiated SM threads exchanged through the patient portal website or app over 1 year (June 1, 2021-May 31, 2022) at 21 Kaiser Permanente Northern California oncology practices, which typically do not have patient copayments associated with SM.
Background: The ECOG performance status (PS) scale was developed to support national clinical trials, but the degree to which ECOG PS predicts clinical outcomes in patient subgroups outside of clinical trials is relatively unknown. This study examined associations between ECOG PS and adverse outcomes in a diverse community oncology population.
Patients And Methods: In this retrospective cohort study, demographic and clinical characteristics, including the most recent ECOG PS between January 1, 2017, and December 31, 2019, were examined for patients receiving cancer treatment within Kaiser Permanente Northern California (KPNC).
Article Synopsis
- Thermal epiglottitis is a rare, non-infectious cause of airway obstruction that mimics symptoms of infectious epiglottitis, observed in a study of pediatric cases over 16 years in southern Israel.
- Among nearly 600,000 pediatric ER visits, only seven cases were diagnosed, primarily affecting very young boys, with symptoms like stridor and respiratory distress; most were treated with steroids and antibiotics.
- The study concludes that thermal epiglottitis should be considered in children with acute airway obstruction, emphasizing the need to ask about accidental hot beverage ingestion, especially when there's no fever or inflammatory markers.
Background: Hospital-acquired venous thromboembolism (HA VTE) is a preventable complication in hospitalized patients.
Objective: We aimed to examine the use of pharmacologic prophylaxis (pPPX) and compare two risk assessment methods for HA VTE: a retrospective electronic Padua Score (ePaduaKP) and admitting clinician's choice of risk within the admission orderset (low, moderate, or high).
Design, Settings And Participants: We retrospectively analyzed prophylaxis orders for adult medical admissions (2013-2019) at Kaiser Permanente Northern California, excluding surgical and ICU patients.