[Pathomorphological features of baby shaking syndrome].

The aim of study is to identify pathomorphological changes of the Central nervous system in childhood with rarely diagnosed of «baby shaking» syndrome on the example of sectional case. The analysis of medical documentation (medical history and outpatient card of the child) was done. The standard method of opening the skull cavity of infants was used.

Histamine releasing activity of blood mononuclear cells is acquired by means of activation of mast cells.

It has been shown that peripheral blood mononuclear cells (PBMC) obtained from atopic patients with acute clinical manifestations of pollinosis, atopic dermatitis or bronchial asthma, and preincubated in vitro for 18 hours, acquired the ability to induce histamine release from auto-basophils and basophils of healthy donors. Both PBMC and their supernatants possessed this histamine releasing activity (HRA). During remission, HRA could be reproduced in sensitive patients after positive cutaneous tests with a specific allergen.

Evidence for thymus involvement in development of adrenal and gonadal endocrine functions in mice.

The endocrine function of the gonads and adrenals was studied in mice with congenital athymia (mutation nude); in normal mice thymectomized at 3 days of age and in congenitally athymic mice with thymic transplants from the 5th day of life. The data demonstrated that abnormal function of the adrenals and testes in nude mice is related to the absence of a functionally active thymus during early ontogenesis. The effect of thymosin (fraction 5) on the formation of adrenal functional activity was studied in congenitally athymic and normal mice.