Publications by authors named "E M Greenblatt"
Article Synopsis
- Recent studies show that there is a lack of awareness among Canadian women about the benefits of folic acid (FA) supplementation before pregnancy, particularly using data from the 2017-2018 Canadian Community Health Survey.
- Approximately 22.1% of women reported being unaware of the benefits of FA.
- Factors such as lower education levels, lack of access to healthcare, low household income, and immigrant status were linked to higher rates of unawareness, highlighting the need for targeted public health campaigns addressing social disadvantages.
In Brief: This point of view article focuses on the potential contribution of defects in protein synthesis (translation) to the incidence of oocyte meiotic failure. We discuss the potential cause of diminished oocyte translation during aging and the impact of these deficits on the function of the meiotic spindle.
Abstract: Errors during female meiosis lead to embryonic aneuploidy and miscarriage and occur with increasing frequency during aging.
Article Synopsis
- The study aimed to assess maternal serum levels of placental growth factor (PlGF), ultrasound placental parameters, and clinical outcomes in IVF frozen embryo transfer (FET) pregnancies, comparing those with and without embryo trophectoderm biopsy.
- Results showed that median PlGF levels were lower in the FET biopsy group (614.5 pg/mL) compared to the non-biopsy group (717.0 pg/mL), although this difference was not statistically significant.
- The conclusion suggests a potential link between trophectoderm biopsy and lower PlGF levels, highlighting the need for further research on its impact on placental health.
Article Synopsis
- Researchers discovered a potential treatment called BLU-782, a small-molecule inhibitor that selectively targets ALK2, effectively blocking its dysregulated signaling in lab tests.
- In mouse studies, BLU-782 demonstrated the ability to prevent unwanted bone formation following injury, suggesting it could be a viable preventative treatment for individuals with FOP.
Purpose: To explore if a day 7 blastocyst is predictive of the reproductive potential of sibling day 5 or day 6 blastocysts?
Methods: Retrospective cohort of autologous frozen embryo transfers (FET), February 2019 to April 2022. Cycles divided into groups 1 to 5, according to the day of embryo cryopreservation and the presence of a day 7 blastocyst sibling within the cohort: group 1/group 2-day 5 blastocyst without/with a day 7 sibling, group 3/group 4-day 6 blastocyst without/with a day 7 sibling, group 5-day 7 blastocyst. Clinical, ongoing pregnancy and miscarriage rates, cycle, and patient characteristics are reported.