Publications by authors named "E M Florida"
Background And Aims: Vitamin D binding protein (DBP) serves a dual function as a vitamin D carrier and actin scavenger. Free DBP is present in high concentrations in serum, while a smaller pool is bound to lipoproteins like HDL and VLDL. The role of DBP's interaction with lipoproteins remains unclear.
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- Psoriasis (PSO) is a chronic autoimmune disease linked to increased risks of heart problems, and this study investigates inflammatory markers in PSO patients, specifically focusing on oxidized mtDNA (ox-mtDNA).
- * Patients with PSO showed higher levels of ox-mtDNA compared to healthy individuals, and these levels were correlated with inflammation markers and negatively associated with good cholesterol levels.
- * Treatment with anti-IL-17a in PSO patients led to decreases in ox-mtDNA and coronary artery issues over a year, suggesting ox-mtDNA could be an important early indicator of heart disease related to autoimmune activity.
Background: Psoriasis is a chronic inflammatory condition associated with coronary artery disease risk. Uptake of oxidized low-density lipoprotein by the lectin-like low-density lipoprotein receptor-1 triggers release of the soluble extracellular domain of the receptor (sLOX-1). We sought to characterize the relationship between sLOX-1, inflammation, and coronary plaque progression in psoriasis.
View Article and Find Full Text PDFBackground: s: Psoriasis is a disease of systemic inflammation associated with increased cardiometabolic risk. Epicardial adipose tissue (EAT) and thoracic adipose tissue (TAT) are contributing factors for atherosclerosis and cardiac dysfunction. We strove to assess the longitudinal impact of the EAT and TAT on coronary and cardiac characteristics in psoriasis.
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