Publications by authors named "E M Fabricius"

Article Synopsis
  • High birth weight and gestational diabetes are linked to an increased risk of obstetric anal sphincter injury during childbirth, as previous studies suggest.
  • A systematic review and meta-analysis of twelve cohort studies showed a slightly higher prevalence of this injury in women with gestational diabetes (2.40%) compared to those without (2.31%).
  • The findings indicate that primiparous women (first-time mothers) with gestational diabetes have a significantly higher risk of injury (6.65%) compared to their counterparts without diabetes, while this risk is not as pronounced in multiparous women (those who have given birth before).
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Background And Objectives: Higher fruit and vegetable intake is associated with lower cardiovascular and all-cause mortality in the general population. It is unclear whether this association occurs in patients on hemodialysis, in whom high fruit and vegetable intake is generally discouraged because of a potential risk of hyperkalemia. We aimed to evaluate the association between fruit and vegetable intake and mortality in hemodialysis.

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Article Synopsis
  • A study was conducted to evaluate how different dietary patterns impact survival rates among adults undergoing hemodialysis, focusing specifically on cardiovascular and overall mortality.
  • The research involved 8,110 participants from a multinational dialysis network and identified two main dietary patterns: "fruit and vegetable" and "Western".
  • Results showed that a higher adherence to the "fruit and vegetable" pattern was associated with lower risks of both cardiovascular and all-cause mortality compared to the "Western" pattern, indicating that diet can play a significant role in patient outcomes.
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Mediterranean and Dietary Approaches to Stop Hypertension (DASH) diets associate with lower cardiovascular and all-cause mortality in the general population, but the benefits for patients on hemodialysis are uncertain. Mediterranean and DASH diet scores were derived from the GALEN Food Frequency Questionnaire within the DIET-HD Study, a multinational cohort study of 9757 adults on hemodialysis. We conducted adjusted Cox regression analyses clustered by country to evaluate the association between diet score tertiles and all-cause and cardiovascular mortality (the lowest tertile was the reference category).

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Background & Aims: Patients on hemodialysis suffer from high risk of premature death, which is largely attributed to cardiovascular disease, but interventions targeting traditional cardiovascular risk factors have made little or no difference. Long chain n-3 polyunsaturated fatty acids (n-3 PUFA) are putative candidates to reduce cardiovascular disease. Diets rich in n-3 PUFA are recommended in the general population, although their role in the hemodialysis setting is uncertain.

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