A Closed-Loop Ear-Worn Wearable EEG System with Real-Time Passive Electrode Skin Impedance Measurement for Early Autism Detection.

Autism spectrum disorder (ASD) is a chronic neurological disorder with the severity directly linked to the diagnosis age. The severity can be reduced if diagnosis and intervention are early (age < 2 years). This work presents a novel ear-worn wearable EEG system designed to aid in the early detection of ASD.

Analogue circuit realisation of surface-confined redox reaction kinetics.

The literature on voltammetry and electrochemical impedance spectroscopy (EIS) recognises the importance of using large-amplitude sinusoidal perturbations to better characterise electrochemical systems. To identify the parameters of a given reaction, various electrochemical models with different sets of values are simulated and compared against the experimental data to determine the best-fit set of parameters. However, the process of solving these nonlinear models is computationally expensive.

Feasibility of mapping and ablating ectopy-triggering ganglionated plexus reproducibly in persistent atrial fibrillation.

Background: Ablation of autonomic ectopy-triggering ganglionated plexuses (ET-GP) has been used to treat paroxysmal atrial fibrillation (AF). It is not known if ET-GP localisation is reproducible between different stimulators or whether ET-GP can be mapped and ablated in persistent AF. We tested the reproducibility of the left atrial ET-GP location using different high-frequency high-output stimulators in AF.

Immunohistochemical characteristics of local sites that trigger atrial arrhythmias in response to high-frequency stimulation.

Aims: The response to high frequency stimulation (HFS) is used to locate putative sites of ganglionated plexuses (GPs), which are implicated in triggering atrial fibrillation (AF). To identify topological and immunohistochemical characteristics of presumed GP sites functionally identified by HFS.

Methods And Results: Sixty-three atrial sites were tested with HFS in four Langendorff-perfused porcine hearts.

A shortened surface electromyography recording is sufficient to facilitate home fasciculation assessment.

Introduction/aims: Fasciculations are an early clinical hallmark of amyotrophic lateral sclerosis (ALS), amenable to detection by high-density surface electromyography (HDSEMG). In conjunction with the Surface Potential Quantification Engine (SPiQE), HDSEMG offers improved spatial resolution for the analysis of fasciculations. This study aims to establish an optimal recording duration to enable longitudinal remote monitoring in the home.