Publications by authors named "E M Bond"
Article Synopsis
- - The study focused on evaluating the effectiveness of a specialized humeral diaphyseal cement restrictor during cemented total shoulder arthroplasty to improve cement pressurization and prevent improper extension.
- - It included 218 shoulders from 207 patients, with results showing that 81.7% of devices were stable in the medullary canal, and stability was better in primary surgeries (84.2%) compared to revision surgeries (64.3%).
- - The quality of cement mantle was also assessed, with 69.7% achieving Barrack grade A quality, significantly higher in primary cases (74.2%) compared to revision cases (39.3%).
Background: The Children's Oncology Group (COG)-AALL0434 trial investigated the addition of nelarabine to the augmented Berlin-Frankfurt-Münster (aBFM) protocol in patients (1.0-30.99 years) with newly diagnosed T-cell acute lymphoblastic leukemia (T-ALL).
View Article and Find Full Text PDFThe neurodevelopmental epoch from fetal stages to early life embodies a critical window of peak growth and plasticity in which differences believed to be associated with many neurodevelopmental and psychiatric disorders first emerge. Obtaining a detailed understanding of the developmental trajectories of the cortical gray matter microstructure is necessary to characterize differential patterns of neurodevelopment that may subserve future intellectual, behavioral, and psychiatric challenges. The neurite orientation dispersion density imaging (NODDI) Gray-Matter Based Spatial Statistics (GBSS) framework leverages information from the NODDI model to enable sensitive characterization of the gray matter microstructure while limiting partial volume contamination and misregistration errors between images collected in different spaces.
View Article and Find Full Text PDFBackground: Hill-Sachs lesions are common after shoulder instability, and treatment options vary but include remplissage or implantation of structural bone graft. Large Hill-Sachs lesions not addressed by remplissage are challenging to manage and may frequently require an open surgical approach for bone filling treatment options. The optimal approach to maximize visualization of the humeral head during these procedures remains unclear.
View Article and Find Full Text PDFEvaluation of Real-World Tumor Response Derived From Electronic Health Record Data Sources: A Feasibility Analysis in Patients With Metastatic Non-Small Cell Lung Cancer Treated With Chemotherapy.
JCO Clin Cancer Inform
August 2024
Article Synopsis
- - The collaboration aimed to analyze real-world data (RWD) to better understand treatment responses in metastatic non-small cell lung cancer (mNSCLC) patients, particularly focusing on the challenges of assessing real-world treatment outcomes.
- - A retrospective observational study was conducted using data from several electronic health record companies that included information from 200 patients treated with a standard chemotherapy protocol, assessing key response metrics such as real-world response rate and overall survival.
- - Results indicated that while clinician assessments were consistent across data sources, there was variability in imaging data and the duration of response; overall, the study confirmed the potential to harmonize diverse data sources for evaluating treatment responses in mNSCLC patients.