Publications by authors named "E M Bendel-Stenzel"

Article Synopsis
  • Limited data exist regarding the effects of cardiac surgery on pregnant individuals and their fetuses, prompting a study reviewing cases from 1978 to 2023.
  • The study analyzed 29 pregnant patients undergoing cardiac surgery, revealing a maternal death rate of 3% and a fetal loss rate of 17%, with higher mortality in those undergoing surgery later in pregnancy.
  • The findings suggest that cesarean delivery before surgery may help reduce fetal mortality if the fetus is viable, highlighting the need for careful planning in such cases.
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Objective:  This study aimed to determine the prevalence and heteroplasmy level(s) of variants m.1555A > G and m.1494C > T, which are associated with aminoglycoside-induced hearing loss, in a general perinatal population.

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Importance: Early anhydramnios during pregnancy, resulting from fetal bilateral renal agenesis, causes lethal pulmonary hypoplasia in neonates. Restoring amniotic fluid via serial amnioinfusions may promote lung development, enabling survival.

Objective: To assess neonatal outcomes of serial amnioinfusions initiated before 26 weeks' gestation to mitigate lethal pulmonary hypoplasia.

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There is a broad phenotypic spectrum of monogenic polycystic kidney diseases (PKDs). These disorders often involve cilia-related genes and lead to the development of fluid-filled cysts and eventual kidney function decline and failure. Preimplantation genetic testing for monogenic (PGT-M) disorders has moved into the clinical realm.

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