Publications by authors named "E M B P Ekanayake"
Background; Turmeric starch (TS) has gained significant attention due to its potential health benefits. Rich in resistant starch (RS) and higher in phosphorus, TS is anticipated to possess properties of high-phosphorus-type RS. Objectives; To understand the host physiology of TS, this study investigated the dose-dependent effects of TS on colonic fermentation in rats.
View Article and Find Full Text PDFSequencing of messenger RNA (mRNA) found in extracellular vesicles (EVs) in liquid biopsies can provide clinical information such as somatic mutations, resistance profiles and tumor recurrence. Despite this, EV mRNA remains underused due to its low abundance in liquid biopsies, and large sample volumes or specialized techniques for analysis are required. Here we introduce Self-amplified and CRISPR-aided Operation to Profile EVs (SCOPE), a platform for EV mRNA detection.
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- Estimation of plant community composition, aboveground biomass, and carbon stock is essential for understanding and managing forest ecosystems, especially in the context of restoration efforts.
- This study, conducted in Sri Lanka over six years, compared community-based forest restoration (CBFR) with state-managed forests by sampling 180 plots and assessing tree diversity, biomass, and carbon storage.
- Results indicated that while state-managed restoration blocks generally had higher biomass and carbon density, certain community-managed areas showed significant potential, suggesting that involving local communities can enhance forest restoration outcomes.
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- Glioma is the most common brain tumor in adults, and current methods for classifying it rely on molecular changes like IDH1.R132H, which can be risky and may not fully capture the complexity of the tumor.
- A new liquid biopsy test called mt-IDH1 is introduced, allowing for a minimally invasive blood test that detects tumor RNA using just 2 ml of plasma.
- In a study with 133 participants, the mt-IDH1 test showed a sensitivity of 75% and specificity of 88.7%, proving its potential for diagnosis and monitoring of gliomas, with results available in under 4 hours.
Background: Cardiovascular Diseases (CVD) account for the highest number of deaths and disability globally and within Sri Lanka. A CVD risk prediction tool is a simple means of early identification of high-risk groups which is a cost-effective preventive strategy, especially for resource-poor countries. Distribution of risk factor levels varies in different regions even within the same country, thus a common risk estimation tool for the country may give false local predictions.
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