Publications by authors named "E Luther"
Vein of Galen malformations (VOGMs) are rare and complex congenital vascular anomalies that can lead to severe morbidity and mortality. Management predominantly focuses on postnatal endovascular interventions. However, these may not be feasible for fetuses with hemodynamic instability and high-output cardiac failure and may fail to prevent irreversible brain damage induced by prolonged compression by the venous varix, hemodynamic alterations and resultant potential ischemic injury.
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- Disulfiram, a medication previously used for alcohol addiction, is being studied as a cancer treatment due to its ability to inhibit cancer cell growth and enhance the effectiveness of chemotherapy and radiation.
- The drug induces apoptosis (cell death) in cancer cells and can be effective against various types of cancer, including breast and prostate cancer.
- Researchers are focusing on new delivery systems, like polycaprolactone-based nanocapsules, which improve the drug's stability and cytotoxicity, suggesting a promising avenue for more effective and safer cancer treatments.
Article Synopsis
- Epidural arteriovenous fistulas (eAVFs) are rare vascular issues often confused with intradural ones, impacting treatment and outcomes.
- A case of a 68-year-old man initially diagnosed with a likely intradural fistula was actually found to have an epidural lesion during surgery, leading to significant improvement after treatment.
- The findings emphasize the need for better imaging techniques and a collaborative medical approach to accurately identify and treat spinal vascular malformations.
The Barriers and Facilitators of Shared Decision Making in Pediatric Otolaryngology: A Qualitative Study.
Otolaryngol Head Neck Surg
January 2025
Objective: To identify barriers and facilitators to implementing shared decision making (SDM) in pediatric otolaryngology.
Study Design: A qualitative study.
Setting: Semistructured interviews of pediatric otolaryngologists.
Article Synopsis
- * A multicenter analysis involved 269 patients, reporting a high success rate (100% effective distal penetration), a low complication rate (2.2%), and significant improvements in cSDH diameter and neurological function at 60-day follow-up.
- * The findings suggest that using MMA embolization with the n-BCA D5W push technique is a safe and viable option alongside or instead of traditional surgery, showing a reduction in recurrence