Publications by authors named "E Lo Turco"

Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections (PANDAS) and Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) are broad diagnoses that encompass a range of sudden-onset neuropsychiatric symptoms in children, which can include obsessive-compulsive disorder (OCD), tics, anxiety, emotional instability, and cognitive difficulties. Unlike PANDAS, PANS is not strictly linked to group A streptococcal infections but can be triggered by various infectious or environmental factors. Lights and shadows remain upon the management of children with PANS and PANDAS and there is no clear consensus regarding definition, diagnostic criteria, treatment, and follow-up.

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Precision nutrition, an expanding field at the intersection of nutrition science and personalized medicine, is rapidly evolving with metabolomics integration. Metabolomics, facilitated by advanced technologies like mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy, facilitates comprehensive profiling of metabolites across diverse biological samples. From the perspective of health care systems, precision nutrition gains relevance due to the substantial impact of prevalent non-communicable diseases (NCDs) on societal well-being, which is directly linked with dietary habits and eating behavior.

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Article Synopsis
  • Phenalenyl (CH) is a type of nanographene that features a unique open-shell structure with spin-1/2 properties, revealing interesting electrical behavior when studied through techniques like STM-IETS.
  • Researchers have discovered that the exchange interactions in phenalenyl dimers can be adjusted by changing the angle between the two molecules, which can lead to different electronic properties.
  • The study employs various theoretical approaches, including density functional theory, to explore ways to manipulate twisting in these dimers, potentially enabling control over magnetic couplings in carbon-based structures.
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  • Brain size and neural cell diversity depend on how multipotent neural progenitor cells (NPCs) grow and specialize, with mistakes in this process causing hereditary microcephaly (MCPH), which leads to smaller brain sizes and intellectual disabilities.
  • Research identified specific genetic variants related to MCPH, but the exact role of CIT protein activity in brain development was unclear, prompting the creation of mouse models for study.
  • Findings revealed that while the mouse models didn't mimic human microcephaly, they did show signs of cell damage and abnormalities; human organoids created from the models exhibited loss of structural complexity and issues with cell division, highlighting the importance of CIT functions in human brain development.
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In the pursuit of high-spin building blocks for the formation of covalently bonded 1D or 2D materials with controlled magnetic interactions, -electron magnetism offers an ideal framework to engineer ferromagnetic interactions between nanographenes. As a first step in this direction, we explore the spin properties of ferromagnetically coupled triangulenes-triangular nanographenes with spin . By combining in-solution synthesis of rationally designed molecular precursors with on-surface synthesis, we successfully achieve covalently bonded triangulene dimers and trimers on Au(111).

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