Prognostic performance of the Bova, sPESI, and Qanadli scores in patients with acute pulmonary embolism.

Background: Acute pulmonary embolism (PE) is a disease with a serious prognosis and a high probability of death in the emergency department.

Purpose: To investigate the prediction of PE-related mortality and intensive care admission (ICU) of Qanadli (Qscore), Bova, and simplified Pulmonary Embolism Severity Index (sPESI) scores.

Material And Methods: This retrospective observational study consisted of all patients diagnosed with acute PE who were imaged under computed tomography pulmonary angiography (CTPA) for a total of 5 years between 1 June 2018 and 1 June 2023.

Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6: A Preliminary Report from Istanbul.

Hand, foot, and mouth disease (HFMD) is caused by various serotypes of genus. Coxsackievirus A16 (CV-A16) and enterovirus A71 (EV-A71) were known to be the only responsible agents for these epidemics; however, this opinion was challenged after the detection that coxsackievirus A6 (CV-A6) was the responsible species for the outbreak in Finland in 2008. HFMD is frequently seen in Turkey, and no detailed study on its clinical and microbiological epidemiology has previously been reported.

Mid-term oral isotretinoin therapy causes a predominantly sensory demyelinating neuropathy.

Background And Purpose: The purpose of this prospective study was to investigate whether mid-term treatment with oral isotretinoin may impact peripheral nerve function.

Methods: In this study, we included 28 patients with no apparent neurological or neurophysiological findings. The patients received treatment with oral isotretinoin for papulopustular or nodulocystic acne.

The human brain from above: an increase in complexity from environmental stimuli to abstractions.

Contrary to common belief, the brain appears to increase the complexity from the perceived object to the idea of it. Topological models predict indeed that: (a) increases in anatomical/functional dimensions and symmetries occur in the transition from the environment to the higher activities of the brain, and (b) informational entropy in the primary sensory areas is lower than in the higher associative ones. To demonstrate this novel hypothesis, we introduce a straightforward approach to measuring island information levels in fMRI neuroimages, via Rényi entropy derived from tessellated fMRI images.