Publications by authors named "E Lepri"
This study describes the congenital goiter in an alpaca (Vicugna pacos) fetus aborted in November 2021 with the clinical and pathological findings in the dam that was found dead on the farm three weeks after a miscarriage. The dam was a black coat alpaca bred in the Netherlands, imported in Italy in January 2021, and housed in a farm of central Italy for breeding purposes. Signalment and clinical data on dam and fetus were collected from the farmer and referring veterinarian.
View Article and Find Full Text PDFAssessing the pathogenicity of a disease-associated genetic variant in animals accurately is vital, both on a population and individual scale. At the population level, breeding decisions based on invalid DNA tests can lead to the incorrect inclusion or exclusion of animals and compromise the long-term health of a population, and at the level of the individual animal, lead to incorrect treatment and even life-ending decisions. Criteria to determine pathogenicity are not standardized, i.
View Article and Find Full Text PDFMTs are prevalent in dogs, representing the most frequent oral malignancy, compared to cats, in which ocular melanomas predominate. This study investigates the canine and feline MT epidemiology (2005-2024) of cases submitted to the Veterinary Pathology Service (University of Perugia). Among the canine neoplasms, 845 (4%) were melanocytic: 329 (39%) melanocytomas; 512 (61%) melanomas.
View Article and Find Full Text PDFArticle Synopsis
- - Feline primary hypertrophic cardiomyopathy (HCM) is a heart disease involving thickening of the left ventricle, and this study focused on the regulatory roles of microRNAs and mRNAs in affected cat heart tissue.
- - Researchers analyzed the expression of key sarcomeric genes in heart tissues from both primary and secondary HCM cats and found significant differences in gene expression, particularly an increase in several genes in primary HCM cases.
- - While the study does not fully uncover the causes of HCM, it highlights the significance of specific microRNAs and their potential in assisting with the diagnosis and prognosis of the disease in feline patients.
Article Synopsis
- The study investigates the role of ticks as potential vectors in the transmission of contagious agalactia (CA) in sheep and goats, a disease that significantly impacts the dairy industry.
- Researchers used immunohistochemistry to analyze the presence of the pathogen in the salivary glands and ovaries of infected ticks, finding strong evidence of the pathogen localization in these tissues.
- This research marks the first time the pathogen has been shown to cross the tick midgut barrier and infect organs that could facilitate disease spread, indicating the need for further studies to confirm hard ticks' involvement in CA transmission.