Publications by authors named "E Lefevre"
Mu opioid receptors in the nucleus accumbens regulate motivated behavior, including pursuit of natural rewards like social interaction as well as exogenous opioids. We used a suite of genetic and viral strategies to conditionally delete mu opioid receptor expression from all major neuron types in the nucleus accumbens. We pinpoint inhibitory interneurons as an essential site of mu opioid receptor expression for typical social behavior, independent from exogenous opioid sensitivity.
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- Cranial dural arteriovenous fistulas (DAVFs) are associated with a higher risk of hemorrhage compared to spinal DAVFs, potentially due to the structural differences in veins.
- The study examined 24 cerebral and 13 spinal veins from cadavers, finding that cerebral veins are larger in diameter but similar in wall thickness compared to spinal veins, leading to a greater diameter-to-thickness ratio.
- This structural difference in veins may affect their pressure resistance, along with variations in pressure gradients and blood flow dynamics contributing to the differing clinical outcomes between cranial and spinal DAVFs.
Vestibular schwannoma surgery in the ninth decade of life: a case series.
Acta Neurochir (Wien)
September 2024
Article Synopsis
- This study evaluates the surgical outcomes of patients aged 80 and older who underwent surgery for large vestibular schwannomas (VS).
- Thirteen patients were examined, with most experiencing good facial function post-surgery and a low rate of serious complications.
- The findings suggest that older age should not automatically prevent patients from undergoing VS surgery, and that planned partial resection is a viable option for elderly patients.
Traumatic intracranial aneurysm (TICA) is a rare and aggressive pathology that requires prompt treatment. Nevertheless, early vascular imaging following head trauma may yield falsely negative results, underscoring the importance of subsequent imaging within the first week to detect delayed TICAs. This study aims to report our experience with delayed TICAs and highlight the clinical importance of repeated angiographic screening for delayed TICAs.
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