Publications by authors named "E Largent"

A comprehensive evaluation for cognitive impairment should culminate with the communication of the diagnosis to patients and their care partners. This diagnostic disclosure sets the stage for subsequent care. Diagnostic disclosure for individuals with cognitive impairment due to Alzheimer's disease (AD) or AD-related dementias (ADRD) is particularly nuanced and requires a conscientious approach.

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Blood-based biomarkers (BBBMs) for Alzheimer's disease (AD) have the potential to revolutionize the detection and management of cognitive impairment. AD BBBMs are not currently recommended for use in primary care but may soon be as research demonstrates their clinical utility for differential diagnosis and patient management. To prepare for the incorporation of AD BBBMs into primary care, several practical challenges must be addressed.

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Article Synopsis
  • - Alzheimer's disease research registries are vital for finding participants, but enrollment is low among at-risk racial and ethnic groups.
  • - This study uses the Reasoned Action Approach to develop persuasive recruitment messages that target underrepresented groups, with survey data collected from 1,501 adults aged 50-80.
  • - Findings show that attitudes are key motivators for signing up, while social norms and perceived capacity vary among groups, suggesting that tailored messages highlighting societal benefits could boost participation.
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Article Synopsis
  • * The paper emphasizes the importance of addressing disparities like ageism and stigma, especially for minoritized communities, while providing examples of how PPI can be integrated throughout the research process.
  • * Recommendations for researchers include fostering collaborative relationships with communities, starting partnerships early, and ensuring that factors like choice, respect, and inclusion are prioritized.
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