Publications by authors named "E Lantto"
Article Synopsis
- The study investigates the impact of surveillance for intraductal papillary mucinous neoplasms (IPMNs) on patients' health-related quality of life (HRQoL) and anxiety levels.
- A subgroup of 232 out of 899 patients completed HRQoL and anxiety questionnaires before and three months after follow-up, revealing minimal negative effects on their well-being.
- The findings suggest that regular monitoring of patients with IPMNs is manageable and unlikely to significantly worsen their quality of life or anxiety, even as the number of patients under surveillance rises.
Introduction: Finnish companies are legally required to insure their employees against occupational accidents. Insurance companies are then required to submit information about occupational accidents to the Finnish Workers' Compensation Center (TVK), which then publishes occupational accident statistics in Finland together with Statistics Finland. Our objective is to detect silent signals, by which we mean patterns in the data such as increased occupational accident frequencies for which there is initially only weak evidence, making their detection challenging.
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- The study focuses on managing patients with branch duct intraductal papillary mucinous neoplasm (BD-IPMN), noting the need for better surveillance due to the rising number of patients.
- A total of 377 patients were analyzed over an average of 5.4 years, revealing that many had small, stable cysts and 12% had elevated levels of CA 19-9, a cancer marker.
- Findings suggest that patients with cysts under 15 mm that do not grow and have normal CA 19-9 levels may require less frequent imaging, as no cancer or high-grade dysplasia was observed in these cases.
Background: Resection of colorectal cancer (CRC) metastases provides good survival but is probably underused in real-world practice.
Methods: A prospective Finnish nationwide study enrolled treatable metastatic CRC patients. The intervention was the assessment of resectability upfront and twice during first-line therapy by the multidisciplinary team (MDT) at Helsinki tertiary referral centre.
Background: Colorectal cancer liver metastases respond to chemotherapy and targeted agents not only by shrinking, but also by morphologic and metabolic changes. The aim of this study was to evaluate the value of advanced magnetic resonance imaging (MRI) methods in predicting treatment response and survival.
Patients And Methods: We investigated contrast-enhanced MRI, apparent diffusion coefficient (ADC) in diffusion-weighted imaging and H-magnetic resonance spectroscopy (H-MRS) in detecting early morphologic and metabolic changes in borderline or resectable liver metastases, as a response to first-line neoadjuvant or conversion therapy in a prospective substudy of the RAXO trial (NCT01531621, EudraCT2011-003158-24).