Publications by authors named "E Lahner"
Background: First-degree relatives of gastric cancer (GC) patients are known to have an increased risk of developing GC. However, guidelines in low-intermediate incidence regions often lack specific recommendations for managing both asymptomatic and symptomatic relatives at risk.
Aim: This study aimed to evaluate the differences in relevant histological findings (e.
Background: Efficacy of eradication regimens in (Hp) infection is commonly reported with proton pump inhibitors (PPIs). In patients with corpus atrophic gastritis, characterized by impaired acid secretion, PPI treatment is questionable.
Objectives: The current study aimed to assess in clinical practice the tolerability and eradication rate of modified eradication regimens without PPI as first-line treatment in patients with histologically Hp-positive corpus atrophic gastritis.
Background And Aim: Corpus atrophic gastritis (CAG) is defined as autoimmune when the antrum is spared, representing this element a crucial diagnostic criterium of autoimmune gastritis. In contrast, CAG with concomitant antral gastritis (AG), atrophic or non-atrophic, is generally attributed to H. pylori infection.
View Article and Find Full Text PDFObjective: During the last decade, the management of gastric intestinal metaplasia (GIM) has been addressed by several distinct international evidence-based guidelines. In this review, we aimed to synthesise these guidelines and provide clinicians with a global perspective of the current recommendations for managing patients with GIM, as well as highlight evidence gaps that need to be addressed with future research.
Design: We conducted a systematic review of the literature for guidelines and consensus statements published between January 2010 and February 2023 that address the diagnosis and management of GIM.
Article Synopsis
- Autoimmune gastritis (AIG) causes higher gastrin levels, leading to changes in the gastric mucosa and an increased risk of developing gastric polyps.
- A study involving 612 AIG patients over a median of 4 years found that 36.3% developed gastric polyps, with various types identified, including inflammatory and adenomatous types, along with some cases of gastric neuroendocrine neoplasms (gNENs) and adenocarcinomas.
- The findings highlight the need for regular endoscopic monitoring and histopathological assessments in AIG patients due to the significant risk of gastric polyps and related complications.