Publications by authors named "E Lafuente"

Natural polysaccharides with excellent biocompatibility are considered ideal materials for repairing diabetic foot ulcer. However, diabetic foot ulcer is often accompanied by decreased muscle function, even resulting in muscle atrophy. During wound repair, monitoring muscle function at the wound site in real time can identify the decreased muscle strength timely, which is crucial for precise wound rehabilitation.

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Article Synopsis
  • Tumor-associated macrophages (TAMs) play a significant role in the tumor microenvironment of oral squamous cell carcinomas (OSCCs) and primarily originate from circulating monocytes that differentiate locally.
  • Research showed that cell culture media from OSCC cell lines, H413 and TR146, encourages monocytes to become M2 macrophages, which are characterized by high CD163 and CD206 expression and low levels of activation markers.
  • Additionally, the study identified specific soluble proteins in the media that promote this differentiation and linked it to an immunosuppressive profile that hinders T cell activation, shedding light on how OSCCs support tumor growth by altering immune cell behavior.
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Freshwater habitats are frequently contaminated by diverse chemicals of anthropogenic origin, collectively referred to as micropollutants, that can have detrimental effects on aquatic life. The animals' tolerance to micropollutants may be mediated by their microbiome. If polluted aquatic environments select for contaminant-degrading microbes, the acquisition of such microbes by the host may increase its tolerance to pollution.

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Diabetic foot ulcers (DFUs), a prevalent complication of diabetes mellitus, may result in an amputation. Natural and renewable hydrogels are desirable materials for DFU dressings due to their outstanding biosafety and degradability. However, most hydrogels are usually only used for wound repair and cannot be employed to monitor motion because of their inherent poor mechanical properties and electrical conductivity.

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Seasonal differences in insect pigmentation are attributed to the influence of ambient temperature on pigmentation development. This thermal plasticity is adaptive and heritable, and thereby capable of evolving. However, the specific genes contributing to the variation in plasticity that can drive its evolution remain largely unknown.

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