Publications by authors named "E Lacotte"

Objectives: Vedolizumab and ustekinumab are effective in inducing and maintaining corticosteroid-free clinical remission (CFR) in adult patients with inflammatory bowel disease (IBD). This study describes the efficacy and safety of vedolizumab and ustekinumab in pediatric IBD.

Methods: All patients ≤18 years of age with Crohn's disease (CD) or ulcerative colitis (UC) treated with vedolizumab or ustekinumab in three centers in Northern France were followed retrospectively.

View Article and Find Full Text PDF

Objectives: Previous studies have shown rates of surgical resection of up to 41% in stricturing pediatric Crohn's disease (CD). In this retrospective multicenter study, our aims were to identify clinical risk factors and magnetic resonance enterography (MRE) features of small bowel strictures associated with surgery.

Methods: Pediatric patients with symptomatic stricturing small bowel CD (defined as obstructive symptoms or proximal dilatation on MRE) confirmed by MRE between 2010 and 2020 were recruited from 12 French tertiary hospitals.

View Article and Find Full Text PDF

Objectives: We aimed to evaluate the association between proton pump inhibitor (PPI) exposure and nosocomial infection (NI) during PICU stay.

Design: Propensity score matched analysis of a single-center retrospective cohort from January 1, 2017, to December 31, 2018.

Setting: Tertiary medical and surgical PICU in France.

View Article and Find Full Text PDF
Article Synopsis
  • * In a group of 102 patients, 22% were found to have at least one Functional Gastrointestinal Disorder, with 17 patients specifically meeting criteria for IBD-FAPD; gender and age data showed a predominance of boys and an average age of 15 years.
  • * It was discovered that patients with IBD-FAPD experienced more fatigue and reported a lower quality of life compared to those without FAPD, while their parents showed higher anxiety levels; notably, the severity
View Article and Find Full Text PDF