Publications by authors named "E Laan"

Objective: To study genital response and sexual arousal in women with and without PCOS and to assess associations with sex steroid levels.

Design: This observational prospective case control study was conducted from March 2017 until March 2020.

Subjects: Heterosexual women with (n=68) and without PCOS (n=67), aged 18-40 years, in a steady relationship and without any comorbidities.

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Study Question: Does offering the Pleasure&Pregnancy (P&P) programme rather than expectant management improve naturally conceived ongoing pregnancy rates in couples diagnosed with unexplained infertility?

Summary Answer: The P&P programme had no effect on the ongoing pregnancy rates of couples with unexplained infertility.

What Is Known Already: Underpowered studies suggested that face-to-face interventions targeting sexual health may increase pregnancy rates. The impact of an eHealth sexual health programme had yet to be evaluated by a large randomized controlled trial.

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Reservoirs play an important role in relation to water security, flood risk, hydropower and natural flow regime. This study derives a novel dataset with a long-term daily water-balance (reservoir volume, inflow, outflow, evaporation and precipitation) of headwater reservoirs and storage dynamics across the globe. The data is generated using cloud computing infrastructure and a high resolution distributed hydrological model wflow_sbm.

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Objective: Sexual pleasure is central to current understandings of sexual function, health, and wellbeing. In this article, we suggest that we lack a sufficiently specific, yet encompassing, definition of sexual pleasure and that we therefore lack comprehensive assessments of sexual pleasure. We introduce a definition of sexual pleasure and position it centrally in an adapted framework of the sexual response.

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Study Question: What is the relationship of sex steroid levels with sexual function in women with and without polycystic ovary syndrome (PCOS)?

Summary Answer: Women with PCOS reported more sexual dysfunction and more sexual distress compared to those without PCOS, but only few and weak associations between androgen levels and sexual function were observed.

What Is Known Already: The literature shows that women with PCOS report lower levels of sexual function and sexual satisfactionand more sexual distress. Contributing factors seem to be obesity, alopecia, hirsutism, acne, infertility, anxiety, depression, and low self-esteem.

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