Publications by authors named "E L van den Burg"
Frequency-to-Place Mismatch and Cochlear Implant Outcomes by Electrode Type.
JAMA Otolaryngol Head Neck Surg
December 2024
Importance: Speech recognition outcomes with a cochlear implant (CI) are highly variable. One factor suggested to correlate with CI-aided speech recognition is frequency-to-place mismatch, or the discrepancy between the natural tonotopic organization of the cochlea and the electric frequency allocation of the CI electrodes within the patient's cochlea.
Objective: To evaluate the association between frequency-to-place mismatch and speech recognition outcomes in a large cohort of postlingually deafened adult CI users, while controlling for various clinical factors known to be associated with those outcomes.
Article Synopsis
- Cutaneous T-cell lymphomas (CTCL) are the most common type of primary skin lymphoma, primarily affecting the skin but also showing extracutaneous symptoms.
- Primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphoma (pcAECTCL) is a rare, aggressive subtype with poor outcomes and potential for systemic spread, particularly to organs like the lungs and central nervous system.
- A case study is presented of a patient with a persistent rash diagnosed with pcAECTCL, where imaging showed possible gastric involvement, but no definitive evidence of metastasis was found after further examination.
Memory strategies in autistic adults seem to mimic strategies at older age, as both younger autistic and older non-autistic individuals use fewer semantic features in visual memory tasks. Therefore, the current study aims to investigate whether early differences in memory strategies lead to altered age-related effects in autism, particularly whether initial difficulties in strategy use become advantageous at older age (i.e.
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- Research shows that autistic individuals face unique challenges in integrating audiovisual speech, but results vary due to different research methods.
- In a systematic review of 18 studies involving nearly 1,000 participants, autistic individuals exhibited significantly poorer audiovisual integration than non-autistic peers.
- The study recommends future research to focus on larger sample sizes, include more adult participants, and standardize methodologies to reduce inconsistencies in findings.
The lateral amygdala (LA) encodes fear memories by potentiating sensory inputs associated with threats and, in the process, recruits 10-30% of its neurons per fear memory engram. However, how the local network within the LA processes this information and whether it also plays a role in storing it are still largely unknown. Here, using ex vivo 12-patch-clamp and in vivo 32-electrode electrophysiological recordings in the LA of fear-conditioned rats, in combination with activity-dependent fluorescent and optogenetic tagging and recall, we identified a sparsely connected network between principal LA neurons that is organized in clusters.
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