Publications by authors named "E L Savlevich"

The article presents results of quantitative sociological surveys based on original on-line questionnaire that allows to assess professional competence of otorhinolaryngologists in prescribing antibiotics to patients with acute and chronic rhinosinusitis. The professional potential of otorhinolaryngologists within the framework of national security strategy in the field of public health. The pilot approbation was carried out in February-December 2023 by means of quantitative sociological on-line survey of 627 otorhinolaryngologists from 32 subjects of the Russian Federation.

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Article Synopsis
  • Rhinosinusitis affects both children and adults, with differences in anatomy, diagnosis, and treatment; adult paranasal sinuses differ significantly from those of children, with adenoids being a major factor in pediatric cases.
  • Diagnosis of pediatric rhinosinusitis is challenging due to the rarity of endoscopic examinations and the frequent association with viral infections and chronic adenoiditis.
  • DysheLORz, a herbal medicine, has shown effectiveness and safety in treating acute and chronic rhinosinusitis in both age groups, primarily by enhancing immune responses and modulating inflammatory markers.
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Unlabelled: Basis of acute pharyngitis pathogenesis is an inflammatory process at the entrance gate of the infection. Therefore, local immunity study proves to be the most informative. Difficulty in making that type of assessment is lack of generally accepted reference values and biological sampling techniques.

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Unlabelled: Clinical phenotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) are characterized with different inflammation patterns of mRNA expression of cytokines and depend on presence of allergic rhinitis (AR), atopic bronchial asthma (aBA) or nonatopic bronchial asthma (nBA).

Objective: To compare inflammation response in patients with different phenotypes of CRSwNP according to level secretion of the key cytokines in nasal polyp tissue.

Material And Methods: 292 patients with CRSwNP were divided into four phenotypes: group 1 - CRSwNP without respiratory allergy (RA) and without BA; group 2a - CRSwNP+ AR with aBA; group 2b - CRSwNP+AR without aBA; group 3 - CRSwNP+nBA.

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Article Synopsis
  • * The study involved 45 patients with chronic pharyngitis; they were treated with a probiotic strain for 14 days, and their symptoms were assessed using a visual analog scale.
  • * Results showed significant improvement in symptoms like pain when swallowing and a sensation of a foreign body in the throat, with pain severity dropping markedly over the treatment period.
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