Publications by authors named "E L Savier"
Visual information can have different meanings across species and the same visual stimulus can drive appetitive or aversive behavior. The superior colliculus (SC), a visual center located in the midbrain has been involved in driving such behaviors. Within this structure, the wide-field vertical cell (WFV) is a conserved morphological cell-type that is present in species ranging from reptiles to cats (Basso et al.
View Article and Find Full Text PDFThe superior colliculus (SC), a midbrain sensorimotor hub, is anatomically and functionally similar across vertebrates, but how its cell types have evolved is unclear. Using single-nucleus transcriptomics, we compared the SC's molecular and cellular organization in mice, tree shrews, and humans. Despite over 96 million years of evolutionary divergence, we identified ~30 consensus neuronal subtypes, including + neurons that form the SC-pulvinar circuit in mice and tree shrews.
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- Early bifurcation of the common hepatic artery (EBCHA) is a rare anatomical variation found in about 1% of individuals, often overlooked but significant in surgeries related to the liver and pancreas.
- Accidental ligation of the right hepatic artery during procedures like pancreaticoduodenectomy can result in serious complications due to arterial ischemia of the right liver.
- Key imaging signs on CT scans such as two hepatic arteries near the celiac trunk, a retro-portal hepatic artery, and the absence of a right hepatic artery from the superior mesenteric artery can help in early diagnosis of EBCHA, reducing the risk of injury during surgery.
Background: Laparoscopic liver resection (LLR) has been associated with improved patient recovery as well as reduced postoperative adhesions compared to open LR (OLR) and could therefore facilitate redo liver surgery. LLR prior to liver transplantation (LT) is increasingly performed, LT being saved for HCC recurrence. LT is still performed by open surgery due to vascular reconstructions and underlying liver chronic disease.
View Article and Find Full Text PDFObjective: To analyse outcomes after adult right ex-situ split graft liver transplantations (RSLT) and compare with available outcome benchmarks from whole liver transplantation (WLT).
Summary Background Data: Ex-situ SLT may be a valuable strategy to tackle the increasing graft shortage. Recently established outcome benchmarks in WLT offer a novel reference to perform a comprehensive analysis of results after ex-situ RSLT.