[Proliferating cell nuclear antigen of the rat thyroid gland before and after birth].

We were studied the proliferative activity of the thyroid gland's cells of embryo and adult Wistar rats due to using the antiserum against the cell nuclear antigen (PCNA). The 100% of cells in thyroid's embryo was a positive on the 16th, 17th, 18th stages of the embryonic development (stages by Kornegy). The percent of PCNA-positive cells considerably increased to 67% on the 19th stage.

[Changes in glycogen metabolism in hereditary muscular diseases (review)].

Impairments of glycogen metabolism in muscles, which occurred in some types of the glycogen storage disease as well as in hereditary diseases of unestablished biochemical nature are reviewed. Hereditary diseases of animals caused by impairment of glycogen metabolism are considered.

[Properties of human chorion neuraminidase].

Some properties of human chorion neuraminidase were studied. Using n-butanol, a solubilized preparation of neuraminidase with specific activity considerably exceeding the initial activity of the chorion homogenate was obtained. The pH-dependence and substrate specificity of the enzyme towards low molecular weight (sialylglycolipids and sialylglycoproteins) native substrates were examined.

[Disruption of the regulation of glycogen phosphorylation by biogenic amines].

In rats with experimental cardiomyopathy the content of liver glycogen was considerably higher than in controls and the biogenic amines had no activating effect on glycogen phosphorolysis. The activity of monoamine oxidase was lower in experimental animals than in controls. After injections of monoamine oxidase inhibitors to normal rats no activation of phosphorolysis by biogenic amines was observed.