[ERYTHROKARIOCYTES APOPTO- TIC ACTIVITY IN ERYTHROBLASTIC ISLANDS OF RATS BONE MARROW].

The functional activity of bcl-2 andp53 proteins in erythrokariocytes of erythroblastic islands (EI) of various classes of bone marrow belonging to intact rats and animals following an acute blood loss were investigated. It is observed that intact rats had the elevated levels of percent content of bcl-2+ erythrokariocytes in EI of the second maturity class, compared to EI of first maturity class and EI involutionary class, and also less in the EI involutionary class compared to EI 1 and EI 2. The percentage content of p53+ erythrokariocytes in intact rats in the EI 2 class was less than in EI 1 and EI involutionary class, and were nearly the same of EI 1, EI 3, EI involutionary class and EI reconstructed.

[Experience of treatment of pancreatonecrosis in hospital in the extreme north].

Criteria of pancreatonecrosis are described in the article. Clinical and ultrasonic signs, the applied ways of treatment of acute pancreatitis are considered in 715 patients. The methods of treatment of complications of pancreatonecrosis are described.

[Clinically significant anomalies of the carotid arteries].

During 2002-2010 years the authors made more than 14 thousand USDS of the brachycephalic zone arteries. In 32 cases (32 men and 8 women) there were disturbances of blood flow due to local intima dysplasia (hyperplasia) in the zone of bifurcation of the common carotid artery by the detected "pathological valve". Alterations in the bifurcation of the common carotid artery were confirmed by angiographic investigation.

[Erythropoietin possible influence on the cellular renovation processes of exocervical epithelium in norm, in case of chronic cervicitis and cervical intraepithelial neoplasia 1 and 2].

The blood plasma erythropoietin content, erythropoietin content, erythropoietin and cellular renovation markers expression in exocervical epithelium in reproductive aged women with normal peripheral red blood values were studied. It was determined that erythropoietin expression increased in exocervical epithelium activity (cervical intraepithelial neoplasia 1 and 2), combined with the increase of blood plasma erythropoietin level, activation of pro- and antiapoptosis programs and cellular proliferation processes in cervical epithelium.

[Blood erythropoietin level in female reproductive age (can the reproductive tissue be the source of erythropoietin in blood?)].

Blood erythropoietin level was investigated in females of reproductive age, who had normal peripheral red blood findings. It was determined that blood erythropoietin level was 1.5-2 times higher (20.