Publications by authors named "E L Efremova"
Toxic environmental pollutants pose a health risk for both humans and animals. Accumulation of industrial contaminants in freshwater fish may become a significant threat to biodiversity. Comprehensive monitoring of the impact of environmental stressors on fish functional systems is important and use of non-invasive tools that can detect the presence of these toxicants in vivo is desirable.
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- Yeast have two critical translation termination factors, eRF1 and eRF3, whose mutations lead to the amplification of their mutant alleles, which is vital for cell survival.
- The study used RNA-Seq and proteome analysis to explore how yeast cells adapt to nonsense mutations and found significant gene expression changes affecting the cell cycle.
- The researchers suggest that the adaptation involves a delay in cell cycle progression, particularly at the G2-M transition, resulting in extended S and G2 phases that promote the replication of the mutant alleles.
Transcription factors from the WOX family are well-known regulators of cell proliferation and differentiation in plants. Herein, we focused on several genes from the intermediate clade and checked their impact on somatic embryogenesis using the model legume object . As a result, we show that overexpression not only stimulates somatic embryogenesis in the embryogenic line, as it was shown previously, but can also induce somatic embryogenesis in the non-embryogenic line.
View Article and Find Full Text PDFWOX family transcription factors are well-known regulators of plant development, controlling cell proliferation and differentiation in diverse organs and tissues. Several genes have been shown to participate in regeneration processes which take place in plant cell cultures in vitro, but the effects of most of them on tissue culture development have not been discovered yet. In this study, we evaluated the effects of gene overexpression on the embryogenic callus development and transcriptomic state in .
View Article and Find Full Text PDFTraumatic brain injury (TBI) is one of the leading causes of disability and death worldwide. It is characterized by various molecular-cellular events, with the main ones being apoptosis and damage to axons. To date, there are no clinically effective neuroprotective drugs.
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