Publications by authors named "E L Berson"
Article Synopsis
- Translational biology emphasizes the connection between clinical phenotypes and biological profiles, helping to transform existing clinical data into actionable biological insights.
- Traditional computational tools struggle with small datasets and complex clinical data, but state-of-the-art foundation models can effectively analyze electronic health records (EHR) to generate detailed proteomics profiles for pregnant patients.
- This research identifies a proteomic signature related to gestational diabetes, highlighting the potential of using FM-derived EHR data to enhance disease understanding and improve therapeutic strategies in a more efficient and economical way.
Background: Multiple lines of evidence support peripheral organs in the initiation or progression of Lewy body disease (LBD), a spectrum of neurodegenerative diagnoses that include Parkinson's Disease (PD) without or with dementia (PDD) and dementia with Lewy bodies (DLB). However, the potential contribution of the peripheral immune response to LBD remains unclear. This study aims to characterize peripheral immune responses unique to participants with LBD at single-cell resolution to highlight potential biomarkers and increase mechanistic understanding of LBD pathogenesis in humans.
View Article and Find Full Text PDFBackground: Anesthesiology plays a crucial role in perioperative care, critical care, and pain management, impacting patient experiences and clinical outcomes. However, our understanding of the anesthesiology research landscape is limited. Accordingly, we initiated a data-driven analysis through topic modeling to uncover research trends, enabling informed decision-making and fostering progress within the field.
View Article and Find Full Text PDFArticle Synopsis
- Stanford Health Care serves around 9 million people and has seen significant changes after opening a second hospital in late 2019 and the impact of the COVID-19 pandemic.
- There was a notable increase in both laboratory tests (45%) and anatomic pathology (AP) cases (17%) following the pandemic, linked to a rise in hospital census driven by more emergency department admissions and longer patient stays.
- The hospital reached overcapacity levels of 103% for AP cases and 114% for lab tests, leading to challenges in performing clinical activities, especially surgical procedures, prompting recommendations for improved operational efficiency in the post-pandemic landscape.