Epidemiology of late-onset sepsis in Malaysian neonatal intensive care units, 2015-2020.

Introduction: To determine the epidemiology of blood culture-positive late-onset sepsis (LOS, >72 hours of age) in 44 Malaysian neonatal intensive care units (NICUs).

Materials And Methods: Study Design: Multicentre retrospective observational study using data from the Malaysian National Neonatal Registry.

Participants: 739486 neonates (birthweight ≥500g, gestation ≥22 weeks) born and admitted in 2015-2020.

A Mn(salen)-Based Artificial Metalloenzyme for Nitrene and Oxene Transfer Catalysis.

The development of artificial metalloenzymes (ArMs) offers a potent approach to incorporate non-natural chemical reactions into biocatalysis. Here we report the assembly of Mn(salen)-based ArMs by embedding biotinylated Mn(salen) complexes into streptavidin (Sav) variants. Using commercially available nitrene and oxo transfer reagents, these biohybrid catalysts catalyzed the aziridination of alkenes and oxidation of benzylic C-H bonds with up to 19 and 146 turnover numbers.

Harnessing Janus structures: enhanced internal electric fields in CN for improved H photocatalysis.

Homojunction engineering holds promise for creating high-performance photocatalysts, yet significant challenges persist in establishing and modulating an effective junction interface. To tackle this, we designed and constructed a novel Janus homojunction photocatalyst by integrating two different forms of triazole-based carbon nitride (CN). In this design, super-sized, ultrathin nanosheets of carbon-rich CN grow epitaxially on a nitrogen-rich honeycomb network of CN, creating a tightly bound and extensive interfacial contact area.

Decoding the entropy-stabilized matrix of high-entropy layered double hydroxides: Harnessing strain dynamics for peroxymonosulfate activation and tetracycline degradation.

The current understanding of the mechanism of high-entropy layered double hydroxide (LDH) on enhancing the efficiency of activating peroxymonosulfate (PMS) remains limited. This work reveals that a strong strain effect, driven by high entropy, modulates the structure of FeCoNiCuZn-LDH (HE-LDH) as evidenced by geometric phase analysis (GPA) and density functional theory (DFT) calculations. Compared to FeCoNiZn-LDH and FeCoNi-LDH with weaker strain effects, the high entropy-driven strain effect in HE-LDH shortens metal-oxygen-hydrogen (MOH) bond lengths, allows system to be in a constant steady state during catalysis, reduces the leaching of active M-OH sites, and enhances the adsorption capacity of these sites and the excess strain strength of the interfacial stretches the I of the PMS, facilitates reactive oxygen species (·OH, SO·, O and O·) generation, and thereby improving the efficiency of PMS in degrading tetracycline (TC).

Urea/Thiourea Imine Linkages Provide Accessible Holes in Flexible Covalent Organic Frameworks and Dominates Self-Adaptivity and Exciton Dissociation.

Unraveling the robust self-adaptivity and minimal energy-dissipation of soft reticular materials for environmental catalysis presents a compelling yet unexplored avenue. Herein, a top-down strategy, tailoring from the unique linkage basis, flexibility degree, skeleton electronics to trace-guest adaptability, is proposed to fill the understanding gap between micro-soft covalent organic frameworks (COFs) and photocatalytic performance. The thio(urea)-basis-dominated linkage within benzotrithiophene-based COFs induce the framework contraction/swelling (intralayer micro-flexibility) in response to tetrahydrofuran or water.