Publications by authors named "E Kucharz"
Objective: Patients with diffuse cutaneous systemic sclerosis (dcSSc) frequently show spontaneous improvement of skin fibrosis. Our aim was to examine whether an improvement in skin fibrosis predicts lower likelihood of visceral organ progression and better survival.
Methods: Patients from the European Scleroderma Trials and Research (EUSTAR) cohort with dcSSc, baseline modified Rodnan skin score (mRSS) ≥7, and valid mRSS at 12±3 months follow up were included.
Article Synopsis
- The study aimed to analyze patients with eosinophilic granulomatosis with polyangiitis (EGPA) from the POLVAS registry based on their ANCA status and when they were diagnosed, and compare them to patients with granulomatosis with polyangiitis (GPA) who have elevated eosinophil levels.
- The results indicated that while ANCA-positive and ANCA-negative EGPA patients had similar clinical characteristics, ANCA-negative patients experienced more cardiovascular issues. Moreover, patients diagnosed before 2012 were generally younger and exhibited higher eosinophil counts and more frequent ENT and cardiovascular symptoms.
- The researchers developed a model to differentiate between EGPA and GPA with elevated eosinophils, achieving high