The investigation of structure-activity relationship of polyamine-targeted synthetic compounds from different chemical groups.

The polyamine (PA) metabolism is involved in cell proliferation and differentiation. Increased cellular PA levels are observed in different types of cancers. Products of PA oxidation induce apoptosis in cancer cells.

Magnetization and ferromagnetic resonance in a Fe/Gd multilayer: experiment and modelling.

Static and dynamic magnetic properties of a [Fe(35 Å)/Gd(50 Å)] superlattice are investigated experimentally in the temperature range 5-295 K using SQUID magnetometery and the ferromagnetic resonance (FMR) technique at frequencies 7-38 GHz. The obtained magnetization curves and FMR spectra are analysed theoretically using numerical simulation on the basis of the effective field model. At every given temperature, both static and resonance experimental data can be approximated well within the proposed model.

Effects of female sex hormones on adhesion of Candida albicans yeast-like fungi to the buccal epithelium.

Hormonal regulation of receptor expression and glycogen concentrations in the epithelial cells of the oral cavity remains poorly studied. Adhesion of microorganisms to the vaginal epithelium correlates with their adhesion to the buccal epithelium. Analysis of the correlation between Candida adhesion to the vaginal and buccal epithelium depending on the hormonal status has demonstrated that activity of Candida albicans strains in the buccal epithelium correlates with their adhesion activity in the vaginal epithelium, with the coefficient of correlations (r) reaching 0.

Effects of specific antibodies and immunocompetent cells on tumor growth in passive transfer experiment.

Experiments with passive transfer of immunocompetent cell and serum demonstrated suppression of tumor growth after transfer of splenocytes from animals immunized with Trypanosoma cruzi. The nonspecific constituent of antitumor effect of immunocompetent cells was detected. The previously reported oncoprotective effect of mucins 2 and 3 was not confirmed.

Effect of basal hormone profile on the formation of the vaginal bacterial cenosis in women.

Adhesion activity of L. acidophilus NK1, L. fermentum 90 TS4, and C.