Publications by authors named "E Kravariti"
Article Synopsis
- The study examined how positive, negative, and disorganized psychotic symptom dimensions relate to different clinical and developmental variables, addressing inconsistencies in definition and prior research.
- Results showed that higher symptom scores were linked to poor social adjustment, earlier onset of symptoms, and specific demographic factors, such as ethnicity and gender.
- The findings also suggested a significant familial influence on disorganized symptoms, highlighting the connections between these symptoms and lower premorbid IQ, especially within monozygotic twin pairs.
Article Synopsis
- The study investigates how endophenotypes, which are traits linked to psychosis, connect to genetic factors by examining specific gene sets.
- It analyzed data from 4,506 participants to compute polygenic risk scores related to schizophrenia and bipolar disorder, ultimately measuring their association with seven different endophenotypes.
- Results indicated a significant link between reduced P300 amplitude and higher schizophrenia risk linked to forebrain-related genes, suggesting genetic variants influence early brain development and may heighten psychosis risk in the future.
Background: There are few data on the profile of those with serious mental illness (SMI) admitted to hospital for physical health reasons.
Aims: To compare outcomes for patients with and without an SMI admitted to hospital in England where the primary reason for admission was chronic obstructive pulmonary disease (COPD).
Method: This was a retrospective, observational analysis of the English Hospital Episodes Statistics data-set for the period from 1 April 2018 to 31 March 2019, for patients aged 18-74 years with COPD as the dominant reason for admission.